This photograph of Dennis Hopper, Peter Fonda and Jack Nicholson was taken during the filming of Easy Rider in 1969. The quintessentially American film is remarkable for a number of reasons, one of the most interesting bits of trivia is that real drugs were used during filming, instead of prop-drugs as was the norm.
Once you know this and re-watch the film, a few things click into place.
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Image via Museum of Cinema.